Of unglazed pottery and glomerular sieving

Zeroing in on the albumin glomerular sieving coefficient.

Glomerular filtration rate dependence of sieving of albumin and some neutral proteins in rat kidneys.

The size and charge-selective properties of the glomerular barrier are partly controversial. Glomerular sieving coefficients (theta) for proteins have rarely been determined noninvasively before in vivo. Therefore, theta was assessed vs. glomerular filtration rate (GFR; (51)Cr-EDTA clearance) in intact rats for radiolabeled myoglobin, kappa-dimer, neutral horseradish peroxidase (nHRP), neutral ...

A distributed two-pore model: theoretical implications and practical application to the glomerular sieving of Ficoll.

In the present study, an extended two-pore theory is presented where the porous pathways are continuously distributed according to small- and large-pore mean radii and SDs. Experimental glomerular sieving data for Ficoll were analyzed using the model. In addition, several theoretical findings are presented along with analytic solutions to many of the equations used in distributed pore modeling....

introduction and classification of seljuq pottery

The Seljuq arts is one of the most brilliant and prominent periods in Iranian art history, and considerable progress has been made in all the arts, including the pottery. The possibility of producing white bodies (white clay) due to the lack of kaolin was one of the Iranian potter’s long-standing aspirations. Iranian Seljuq potteries used a new artificial body called stone paste (Bādānehaye Jes...

Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality.

To identify the specific in vivo renal effect of reactive oxygen species (ROS), hydrogen peroxide (H2O2) was infused directly into the left renal artery in Munich-Wistar rats. H2O2 (5 to 50 mumol over 1 h) induced a dose-dependent increase in urine protein excretion rate in infused kidneys, reaching a maximum at the dose of 35 mumol (on average, a 60-fold increase from baseline). The H2O2 (35 m...